{"id":257,"date":"2022-03-19T23:26:43","date_gmt":"2022-03-19T23:26:43","guid":{"rendered":"https:\/\/www.newmrna.eu\/?page_id=257"},"modified":"2025-09-02T06:59:05","modified_gmt":"2025-09-02T06:59:05","slug":"publications","status":"publish","type":"page","link":"https:\/\/www.newmrna.eu\/?page_id=257","title":{"rendered":"Publications"},"content":{"rendered":"\n

Keller J, Danis J, Krehl I, Girousi E, Satoh TK, Meier-Schiesser B, Kem\u00e9ny L, Sz\u00e9ll M, Wong WW,\u00a0Pascolo S<\/strong>, French LE, K\u00fcndig TM, Mellett M LL37 complexed to double-stranded RNA induces RIG-I-like receptor signalling and Gasdermin E activation facilitating IL-36\u03b3\u00a0release from keratinocytes. (2025) Cell Death Dis. 16<\/strong>(1):198 doi: 10.1038\/s41419-025-07537-9<\/a><\/p>\n\n\n\n

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Huber L, Kucera T, H\u00f6llerer S, Borgwardt K, Panke S<\/strong>\u00a0& Jeschek M\u00a0Data-driven protease engineering by DNA-recording and epistasis-aware machine learning. (2025) Nature Comms. 16<\/strong>(1):5466 doi: 10.1038\/s41467-025-60622-7<\/a><\/p>\n\n\n\n

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Mamaghani S, Penna RR, Frei J<\/strong>, Wyss C, Mellett\u00a0M, Look T<\/strong>, Weiss T, Guenova E, K\u00fcndig TM, Lauchli S,\u00a0Pascolo S<\/strong> Synthetic mRNAs Containing Minimalistic Untranslated Regions Are Highly Functional In Vitro and In Vivo (2024) Cells 13<\/strong>(15):1242 doi: 10.3390\/cells13151242<\/a><\/p>\n\n\n\n

Holzinger T, Frei J, Jarzebska NT, Beer HD, K\u00fcndig TM,\u00a0Pascolo S<\/strong>, L\u00e4uchli S, Mellett M Differential functionality of fluoropyrimidine nucleosides for safe cancer therapy. (2024) Anticancer Drugs 35<\/strong>(10):912-921. doi: 10.1097\/CAD.0000000000001644<\/a><\/p>\n\n\n\n

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Blanchard A, Abramov M, Hassan C, Marliere P<\/strong>, Herdewijn P<\/strong> and Pezo, V<\/strong> A microbiological system for screening the interference of XNA monomers with DNA and RNA metabolism. (2023) RSC Advances 13<\/strong>(43):29862-29865. doi: 10.1039\/d3ra06172h <\/a><\/p>\n\n\n\n

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Nguyen, H., Abramov, M., Rozenski, J., Ermeeva, E., Herdewijn, P<\/strong>. In vivo assembly and expression of DNA containing non-canonical bases in the yeast Saccharomyces cerevisiae<\/em>. ChemBioChem 23: e202200060 DOI: 10.1002\/cbic.202200060 <\/p>\n\n\n\n

Ghezzo M, Grigoletto L, Rigo R, Herdewijn P, Groaz E<\/strong>, Sissi C. Modulation of the tetrameric I-motif folding of C-rich Tetrahymena <\/em>telomeric sequences by hexitol nucleic acid (HNA) modifications. Biochimie, 2023, 214:112 DOI: 10.1016\/j.biochi.2023.08.003 <\/p>\n\n\n\n

Yang H, Eremeeva E, Abramov M, Jacquemyn M, Groaz E<\/strong>, Daelemans D, Herdewijn P. CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids. Nucleic Acids Res. 2023 51:1501 DOI: 10.1093\/nar\/gkac1147 <\/p>\n\n\n\n

Pascolo S<\/strong>. Nonreplicating synthetic mRNA vaccines: A journey through the European (Journal of Immunology) history. (2023) Eur J Immunol 53<\/strong>:e2249941.  doi: 10.1002\/eji.202249941<\/a>.<\/p>\n\n\n\n

Jarzebska NT, Tusup M, Frei J\u2026Pascolo S<\/strong> RNA with chemotherapeutic base analogues as a dual-functional anti-cancer drug. (2022) Oncoimmunology 11<\/strong>:2147665. doi.org\/10.1080\/2162402X.2022.2147665<\/a><\/p>\n\n\n\n

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Jarzebska NT, Mellett M, Frei J, K\u00fcndig TM, Pascolo S<\/strong>. Pharmaceutics. (2021) 13<\/strong>:877. doi: 10.3390\/pharmaceutics13060877.<\/a><\/p>\n\n\n\n

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Pascolo S<\/strong>. Cells. (2021) 10<\/strong>:2716. doi: 10.3390\/cells10102716<\/a>.<\/p>\n\n\n\n

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Romano E, Pascolo S<\/strong>, Ott P. J Immunother Cancer. (2021) 9<\/strong>:e002932. doi: 10.1136\/jitc-2021-002932<\/a>.<\/p>\n\n\n\n

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Jarzebska NT, Frei J, Lauchli S, French LE, Guenova E, Gouttefangeas C, K\u00fcndig TM, Mellett M, Pascolo S<\/strong>. Viruses. (2021) 13<\/strong>:1232. doi: 10.3390\/v13071232.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Keller J, Danis J, Krehl I, Girousi E, Satoh TK, Meier-Schiesser B, Kem\u00e9ny L, Sz\u00e9ll M, Wong WW,\u00a0Pascolo S, French LE, K\u00fcndig TM, Mellett M […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-257","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.newmrna.eu\/index.php?rest_route=\/wp\/v2\/pages\/257","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newmrna.eu\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.newmrna.eu\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.newmrna.eu\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newmrna.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=257"}],"version-history":[{"count":16,"href":"https:\/\/www.newmrna.eu\/index.php?rest_route=\/wp\/v2\/pages\/257\/revisions"}],"predecessor-version":[{"id":362,"href":"https:\/\/www.newmrna.eu\/index.php?rest_route=\/wp\/v2\/pages\/257\/revisions\/362"}],"wp:attachment":[{"href":"https:\/\/www.newmrna.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=257"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}