Publications

Keller J, Danis J, Krehl I, Girousi E, Satoh TK, Meier-Schiesser B, Kemény L, Széll M, Wong WW, Pascolo S, French LE, Kündig TM, Mellett M LL37 complexed to double-stranded RNA induces RIG-I-like receptor signalling and Gasdermin E activation facilitating IL-36γ release from keratinocytes. (2025) Cell Death Dis. 16(1):198 doi: 10.1038/s41419-025-07537-9

Huber L, Kucera T, Höllerer S, Borgwardt K, Panke S & Jeschek M Data-driven protease engineering by DNA-recording and epistasis-aware machine learning. (2025) Nature Comms. 16(1):5466 doi: 10.1038/s41467-025-60622-7

Mamaghani S, Penna RR, Frei J, Wyss C, Mellett M, Look T, Weiss T, Guenova E, Kündig TM, Lauchli S, Pascolo S Synthetic mRNAs Containing Minimalistic Untranslated Regions Are Highly Functional In Vitro and In Vivo (2024) Cells 13(15):1242 doi: 10.3390/cells13151242

Holzinger T, Frei J, Jarzebska NT, Beer HD, Kündig TM, Pascolo S, Läuchli S, Mellett M Differential functionality of fluoropyrimidine nucleosides for safe cancer therapy. (2024) Anticancer Drugs 35(10):912-921. doi: 10.1097/CAD.0000000000001644

Blanchard A, Abramov M, Hassan C, Marliere P, Herdewijn P and Pezo, V A microbiological system for screening the interference of XNA monomers with DNA and RNA metabolism. (2023) RSC Advances 13(43):29862-29865. doi: 10.1039/d3ra06172h

Nguyen, H., Abramov, M., Rozenski, J., Ermeeva, E., Herdewijn, P. In vivo assembly and expression of DNA containing non-canonical bases in the yeast Saccharomyces cerevisiae. ChemBioChem 23: e202200060 DOI: 10.1002/cbic.202200060 

Ghezzo M, Grigoletto L, Rigo R, Herdewijn P, Groaz E, Sissi C. Modulation of the tetrameric I-motif folding of C-rich Tetrahymena telomeric sequences by hexitol nucleic acid (HNA) modifications. Biochimie, 2023, 214:112 DOI: 10.1016/j.biochi.2023.08.003 

Yang H, Eremeeva E, Abramov M, Jacquemyn M, Groaz E, Daelemans D, Herdewijn P. CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids. Nucleic Acids Res. 2023 51:1501 DOI: 10.1093/nar/gkac1147 

Pascolo S. Nonreplicating synthetic mRNA vaccines: A journey through the European (Journal of Immunology) history. (2023) Eur J Immunol 53:e2249941.  doi: 10.1002/eji.202249941.

Jarzebska NT, Tusup M, Frei J…Pascolo S RNA with chemotherapeutic base analogues as a dual-functional anti-cancer drug. (2022) Oncoimmunology 11:2147665. doi.org/10.1080/2162402X.2022.2147665

Jarzebska NT, Mellett M, Frei J, Kündig TM, Pascolo S. Pharmaceutics. (2021) 13:877. doi: 10.3390/pharmaceutics13060877.

Pascolo S. Cells. (2021) 10:2716. doi: 10.3390/cells10102716.

Romano E, Pascolo S, Ott P. J Immunother Cancer. (2021) 9:e002932. doi: 10.1136/jitc-2021-002932.

Jarzebska NT, Frei J, Lauchli S, French LE, Guenova E, Gouttefangeas C, Kündig TM, Mellett M, Pascolo S. Viruses. (2021) 13:1232. doi: 10.3390/v13071232.